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DNA methylation-based chromatin compartments and ChIP-seq profiles reveal transcriptional drivers of prostate carcinogenesis

BACKGROUND: Profiles of DNA methylation of many tissues relevant in human disease have been obtained from microarrays and are publicly available. These can be used to generate maps of chromatin compartmentalization, demarcating open and closed chromatin across the genome. Additionally, large sets of...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Simmonds, Poppy, Loomis, Erick, Curry, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463361/
https://ncbi.nlm.nih.gov/pubmed/28592290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0443-z
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