Zebrafish models for functional and toxicological screening of nanoscale drug delivery systems: promoting preclinical applications

Preclinical screening with animal models is an important initial step in clinical translation of new drug delivery systems. However, establishing efficacy, biodistribution, and biotoxicity of complex, multicomponent systems in small animal models can be expensive and time-consuming. Zebrafish models...

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Bibliographic Details
Published in:Biosci Rep
Main Authors: Lee, Keon Yong, Jang, Gun Hyuk, Byun, Cho Hyun, Jeun, Minhong, Searson, Peter C., Lee, Kwan Hyi
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2017
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463258/
https://ncbi.nlm.nih.gov/pubmed/28515222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170199
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