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L1 Cell Adhesion Molecule Promotes Migration and Invasion via JNK Activation in Extrahepatic Cholangiocarcinoma Cells with Activating KRAS Mutation

Extrahepatic cholangiocarcinoma (ECC), a malignant tumor of biliary origin, has a poor prognosis with limited treatment options. The KRAS oncogene is the most commonly mutated gene in ECC and one of the factors that predicts a poor prognosis and low survival rate. L1 cell adhesion molecule (L1CAM) i...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Kim, Haejung, Hwang, Haein, Lee, Hansoo, Hong, Hyo Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463045/
https://ncbi.nlm.nih.gov/pubmed/28535665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.2282
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