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The STI and UBA domains of UBQLN1 are critical determinants of substrate interaction and proteostasis
There are 5 Ubiquilin proteins (UBQLN1-4, UBQLN-L), which are evolutionarily conserved and structurally similar. UBQLN proteins have 3 functional domains: N-terminal ubiquitin-like domain (UBL), C-terminal ubiquitin-associated domain (UBA) and STI chaperone-like regions in the middle. Alterations in...
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| Publicado no: | J Cell Biochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462870/ https://ncbi.nlm.nih.gov/pubmed/28075048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25880 |
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