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Maternal Pre-Pregnancy BMI Downregulates Neonatal Cord Blood LEP Methylation

BACKGROUND: Neonatal adiposity has many determinants and may be a risk factor for future obesity. Epigenetic regulation of metabolically important genes are a potential contributor. OBJECTIVE: To determine whether methylation changes in the LEP gene in cord blood DNA are impacted by the maternal env...

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Bibliografiske detaljer
Udgivet i:Pediatr Obes
Main Authors: Kadakia, Rachel, Zheng, Yinan, Zhang, Zhou, Zhang, Wei, Hou, Lifang, Josefson, Jami L
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462869/
https://ncbi.nlm.nih.gov/pubmed/27933755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ijpo.12204
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