Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients?

Rheumatoid arthritis (RA) is a chronic inflammatory disease of the synovial joints, with progressive destruction of cartilage and bone. Anti-tumour necrosis factor-α therapies (e.g. soluble tumour necrosis factor receptors) ameliorate disease in 60–70% of patients with RA. However, the need for repe...

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Bibliographic Details
Main Authors: van de Loo, Fons AJ, Smeets, Ruben L, van den Berg, Wim B
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC546285/
https://ncbi.nlm.nih.gov/pubmed/15380032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1214
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