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Mitogen-Activated Protein Kinase Phosphatase 1 (MKP-1) in Macrophage Biology and Cardiovascular Disease. A Redox-Regulated Master Controller of Monocyte Function and Macrophage Phenotype

MAPK pathways play a critical role in the activation of monocytes and macrophages by pathogens, signaling molecules and environmental cues and in the regulation of macrophage function and plasticity. MAPK phosphatase 1 (MKP-1) has emerged as the main counter-regulator of MAPK signaling in monocytes...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Kim, Hong Seok, Asmis, Reto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462841/
https://ncbi.nlm.nih.gov/pubmed/28330703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.03.020
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