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Development of a 3D angiogenesis model to study tumour – endothelial cell interactions and the effects of anti-angiogenic drugs

The tumour microenvironment and tumour angiogenesis play a critical role in the development and therapy of many cancers, but in vitro models reflecting these circumstances are rare. In this study, we describe the development of a novel tri-culture model, using non-small cell lung cancer (NSCLC) cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Amann, Arno, Zwierzina, Marit, Koeck, Stefan, Gamerith, Gabriele, Pechriggl, Elisabeth, Huber, Julia M., Lorenz, Edith, Kelm, Jens M., Hilbe, Wolfgang, Zwierzina, Heinz, Kern, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462801/
https://ncbi.nlm.nih.gov/pubmed/28592821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03010-6
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