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Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a.

Complement component C3a is an anaphylatoxin known to induce plasma exudation and smooth muscle contraction in tissues. The effects on inflammatory effector leukocytes, however, are poorly defined and controversial, being at best weak and occurring at very high C3a concentrations. Here, we examined...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bischoff, S C, de Weck, A L, Dahinden, C A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.17.6813
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