Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes

Severe infections like sepsis lead frequently to cardiomyopathy. The mechanisms are unclear and an optimal therapy for septic cardiomyopathy still lacks. The aim of this study is to establish an endotoxin-induced inflammatory model using human induced pluripotent stem cell (hiPSC) derived cardiomyoc...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yücel, Gökhan, Zhao, Zhihan, El-Battrawy, Ibrahim, Lan, Huan, Lang, Siegfried, Li, Xin, Buljubasic, Fanis, Zimmermann, Wolfram-Hubertus, Cyganek, Lukas, Utikal, Jochen, Ravens, Ursula, Wieland, Thomas, Borggrefe, Martin, Zhou, Xiao-Bo, Akin, Ibrahim
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462745/
https://ncbi.nlm.nih.gov/pubmed/28592841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03147-4
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