Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes

Severe infections like sepsis lead frequently to cardiomyopathy. The mechanisms are unclear and an optimal therapy for septic cardiomyopathy still lacks. The aim of this study is to establish an endotoxin-induced inflammatory model using human induced pluripotent stem cell (hiPSC) derived cardiomyoc...

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Publicado en:Sci Rep
Autores principales: Yücel, Gökhan, Zhao, Zhihan, El-Battrawy, Ibrahim, Lan, Huan, Lang, Siegfried, Li, Xin, Buljubasic, Fanis, Zimmermann, Wolfram-Hubertus, Cyganek, Lukas, Utikal, Jochen, Ravens, Ursula, Wieland, Thomas, Borggrefe, Martin, Zhou, Xiao-Bo, Akin, Ibrahim
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462745/
https://ncbi.nlm.nih.gov/pubmed/28592841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03147-4
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