Vitamin K–Dependent Carboxylation of Matrix Gla Protein Influences the Risk of Calciphylaxis

Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification. The ability of MGP to inhibit calcification requires the activity of a vitamin K–dependent enzyme, which mediates MGP carboxylation. We investigated how MGP carboxylation influences the risk of calciphylaxis in adult patients...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Nigwekar, Sagar U., Bloch, Donald B., Nazarian, Rosalynn M., Vermeer, Cees, Booth, Sarah L., Xu, Dihua, Thadhani, Ravi I., Malhotra, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461787/
https://ncbi.nlm.nih.gov/pubmed/28049648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016060651
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