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Osmotic Stress–Induced Defective Glial Proteostasis Contributes to Brain Demyelination after Hyponatremia Treatment

Adequate protein folding is necessary for normal cell function and a tightly regulated process that requires proper intracellular ionic strength. In many cell types, imbalance between protein synthesis and degradation can induce endoplasmic reticulum (ER) stress, which if sustained, can in turn lead...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Gankam-Kengne, Fabrice, Couturier, Bruno S., Soupart, Alain, Brion, Jean Pierre, Decaux, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461785/
https://ncbi.nlm.nih.gov/pubmed/28122966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050509
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