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Therapeutic opportunities and challenges of induced pluripotent stem cells-derived motor neurons for treatment of amyotrophic lateral sclerosis and motor neuron disease

Amyotrophic lateral sclerosis (ALS) and motor neuron diseases (MNDs) are progressive neurodegenerative diseases that affect nerve cells in the brain affecting upper and lower motor neurons (UMNs/LMNs), brain stem and spinal cord. The clinical phenotype is characterized by loss of motor neurons (MNs)...

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Bibliographische Detailangaben
Veröffentlicht in:Neural Regen Res
1. Verfasser: Jaiswal, Manoj Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461603/
https://ncbi.nlm.nih.gov/pubmed/28616022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.206635
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