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Comparative study of sequence-dependent hybridization kinetics in solution and on microspheres

Hybridization kinetics of DNA sequences with known secondary structures and random sequences designed with similar melting temperatures were studied in solution and when one strand was bound to 5 μm silica microspheres. The rates of hybridization followed second-order kinetics and were measured spec...

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Detalles Bibliográficos
Main Authors: Sekar, Michael M. A., Bloch, Will, St John, Pamela M.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC546151/
https://ncbi.nlm.nih.gov/pubmed/15653637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki163
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