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Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β(2)-adrenoceptor clusters assembled by alpha-actinin-4

Neisseria meningitidis (meningococcus) is an invasive bacterial pathogen that colonizes human vessels, causing thrombotic lesions and meningitis. Establishment of tight interactions with endothelial cells is crucial for meningococci to resist haemodynamic forces. Two endothelial receptors, CD147 and...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Maïssa, Nawal, Covarelli, Valentina, Janel, Sébastien, Durel, Beatrice, Simpson, Nandi, Bernard, Sandra C., Pardo-Lopez, Liliana, Bouzinba-Ségard, Haniaa, Faure, Camille, Scott, Mark G.H., Coureuil, Mathieu, Morand, Philippe C., Lafont, Frank, Nassif, Xavier, Marullo, Stefano, Bourdoulous, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461506/
https://ncbi.nlm.nih.gov/pubmed/28569760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15764
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