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Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β(2)-adrenoceptor clusters assembled by alpha-actinin-4
Neisseria meningitidis (meningococcus) is an invasive bacterial pathogen that colonizes human vessels, causing thrombotic lesions and meningitis. Establishment of tight interactions with endothelial cells is crucial for meningococci to resist haemodynamic forces. Two endothelial receptors, CD147 and...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461506/ https://ncbi.nlm.nih.gov/pubmed/28569760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15764 |
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