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Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase
Aspartic acid residues comprising the -D-(aa)(n)-Y-L-D-D- DNA polymerase active site triad of reverse transcriptase from the Saccharomyces cerevisiae long terminal repeat-retrotransposon Ty3 (Asp151, Asp213 and Asp214) were evaluated via site-directed mutagenesis. An Asp151→Glu substitution showed a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546138/ https://ncbi.nlm.nih.gov/pubmed/15647500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki150 |
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