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Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro
Interferon regulatory factor 8 (Irf8) is a transcription factor that negatively regulates osteoclast differentiation and Irf8 global knockout (Irf8 (−/−)) mice have been shown to have reduced bone volume resulting from increased osteoclast numbers. However, detailed analysis of the functions of Irf8...
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| 出版年: | Cytotechnology |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461233/ https://ncbi.nlm.nih.gov/pubmed/27502007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-016-0013-z |
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