Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro

Interferon regulatory factor 8 (Irf8) is a transcription factor that negatively regulates osteoclast differentiation and Irf8 global knockout (Irf8 (−/−)) mice have been shown to have reduced bone volume resulting from increased osteoclast numbers. However, detailed analysis of the functions of Irf8...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Saito, Emi, Suzuki, Dai, Kurotaki, Daisuke, Mochizuki, Ayako, Manome, Yoko, Suzawa, Tetsuo, Toyoshima, Yoichi, Ichikawa, Takahiro, Funatsu, Takahiro, Inoue, Tomio, Takami, Masamichi, Tamura, Tomohiko, Inagaki, Katsunori, Kamijo, Ryutaro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461233/
https://ncbi.nlm.nih.gov/pubmed/27502007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-016-0013-z
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