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Synergistic effect of ascorbic acid and collagen addition on the increase in type 2 collagen accumulation in cartilage-like MSC sheet

Aiming to increase the content of type 2 collagen in scaffold-free cartilage-like cell sheets prepared using human bone marrow mesenchymal stem cells, the effect of several kinds of additives in a chondrogenic medium was investigated. Addition of ascorbic acid 2 phosphate (VCP) at a high concentrati...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Sato, Yasushi, Mera, Hisashi, Takahashi, Daisuke, Majima, Tokifumi, Iwasaki, Norimasa, Wakitani, Shigeyuki, Takagi, Mutsumi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461231/
https://ncbi.nlm.nih.gov/pubmed/26572654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-015-9924-3
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