TNFα promotes proliferation of human synovial MSCs while maintaining chondrogenic potential

Synovial mesenchymal stem cells (MSCs) are a candidate cell source for cartilage and meniscus regeneration. If we can proliferate synovial MSCs more effectively, we can expand clinical applications to patients with large cartilage and meniscus lesions. TNFα is a pleiotropic cytokine that can affect...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Shioda, Mikio, Muneta, Takeshi, Tsuji, Kunikazu, Mizuno, Mitsuru, Komori, Keiichiro, Koga, Hideyuki, Sekiya, Ichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461123/
https://ncbi.nlm.nih.gov/pubmed/28542363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177771
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