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Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment

Kinetochores mediate chromosome congression by either sliding along the lattice of spindle microtubules or forming end-on attachments to their depolymerizing plus-ends. By following the fates of individual kinetochores as they congress in live cells, we reveal that the Ska complex is required for a...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Auckland, Philip, Clarke, Nicholas I., Royle, Stephen J., McAinsh, Andrew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461014/
https://ncbi.nlm.nih.gov/pubmed/28495837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607096
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