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Androgen signaling negatively controls group 2 innate lymphoid cells
Prevalence of asthma is higher in women than in men, but the mechanisms underlying this sex bias are unknown. Group 2 innate lymphoid cells (ILC2s) are key regulators of type 2 inflammatory responses. Here, we show that ILC2 development is greatly influenced by male sex hormones. Male mice have redu...
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Publicado no: | J Exp Med |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461006/ https://ncbi.nlm.nih.gov/pubmed/28484078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161807 |
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