PD-1 regulates KLRG1(+) group 2 innate lymphoid cells

Group 2 innate lymphoid cells (ILC-2s) regulate immune responses to pathogens and maintain tissue homeostasis in response to cytokines. Positive regulation of ILC-2s through ICOS has been recently elucidated. We demonstrate here that PD-1 is an important negative regulator of KLRG1(+) ILC-2 function...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Taylor, Samuel, Huang, Yuefeng, Mallett, Grace, Stathopoulou, Chaido, Felizardo, Tania C., Sun, Ming-An, Martin, Evelyn L., Zhu, Nathaniel, Woodward, Emma L., Elias, Martina S., Scott, Jonathan, Reynolds, Nick J., Paul, William E., Fowler, Daniel H., Amarnath, Shoba
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461001/
https://ncbi.nlm.nih.gov/pubmed/28490441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161653
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