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Of mice and men: in vivo and in vitro studies of primordial germ cell specification
Specification of mouse primordial germ cells (PGCs), the precursors of sperm and eggs, involves three major molecular events: repression of the somatic program; re-acquisition of pluripotency; and reprogramming to a unique epigenetic ground state. Gene knockout studies in mouse models, along with gl...
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Publicado no: | Semin Reprod Med |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460914/ https://ncbi.nlm.nih.gov/pubmed/28278531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1599085 |
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