Cardiac Myosin Binding Protein-C Autoantibodies Are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome

The degradation and release of cardiac myosin binding protein-C (cMyBP-C) upon cardiac damage may stimulate an inflammatory response and autoantibody (AAb) production. We determined whether the presence of cMyBP-C-AAbs associated with adverse cardiac function in cardiovascular disease patients. Impo...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Lynch, Thomas L., Kuster, Diederik W.D., Gonzalez, Beverly, Balasubramanian, Neelam, Nair, Nandini, Day, Sharlene, Calvino, Jenna E., Tan, Yanli, Liebetrau, Christoph, Troidl, Christian, Hamm, Christian W., Güçlü, Ahmet, McDonough, Barbara, Marian, Ali J., van der Velden, Jolanda, Seidman, Christine E., Huggins, Gordon S., Sadayappan, Sakthivel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
CLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460768/
https://ncbi.nlm.nih.gov/pubmed/28596995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2016.12.001
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