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High throughput and sensitive analysis of urinary heterocyclic aromatic amines using isotope-dilution liquid chromatography-tandem mass spectrometry and robotic sample preparation system

Heterocyclic aromatic amines (HCAA) are listed by the US Food and Drug Administration (FDA) as harmful or potentially harmful constituents of tobacco smoke. However, quantifying HCAA exposure is challenging. In this study, we developed a sensitive, precise and accurate isotope dilution, liquid chrom...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Zhang, Li, Xia, Yang, Xia, Baoyun, Nicodemus, Keegan J., McGuffey, James, McGahee, Ernest, Blount, Benjamin, Wang, Lanqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460753/
https://ncbi.nlm.nih.gov/pubmed/27687186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-016-9917-x
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