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Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation

BACKGROUND: Progressive liver fibrosis leads to cirrhosis and end-stage liver disease. This disease is a consequence of strong interactions between matrix-producing hepatic stellate cells (HSCs) and resident and infiltrating immune cell populations. Accumulated experimental evidence supports the inv...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Najimi, Mustapha, Berardis, Silvia, El-Kehdy, Hoda, Rosseels, Valérie, Evraerts, Jonathan, Lombard, Catherine, El Taghdouini, Adil, Henriet, Patrick, van Grunsven, Leo, Sokal, Etienne Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460523/
https://ncbi.nlm.nih.gov/pubmed/28583205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0575-5
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