Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages

BACKGROUND: Cerebral microbleeds (CMB) are MRI-demonstrable cerebral microhemorrhages (CMH) which commonly coexist with ischemic stroke. This creates a challenging therapeutic milieu, and a strategy that simultaneously protects the vessel wall and provides anti-thrombotic activity is an attractive p...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Sumbria, Rachita K., Vasilevko, Vitaly, Grigoryan, Mher Mahoney, Paganini-Hill, Annlia, Kim, Ronald, Cribbs, David H., Fisher, Mark J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460510/
https://ncbi.nlm.nih.gov/pubmed/28583195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0885-7
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