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Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance Mycobacterium tuberculosis peptides in human serum

BACKGROUND: Mycobacterium tuberculosis (Mtb) is the causative agent of Tuberculosis (TB), the number one cause of death due to an infectious disease. TB diagnosis is performed by microscopy, culture or PCR amplification of bacterial DNA, all of which require patient sputum or the biopsy of infected...

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Bibliographic Details
Published in:Clin Proteomics
Main Authors: Mehaffy, Carolina, Dobos, Karen M., Nahid, Payam, Kruh-Garcia, Nicole A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460347/
https://ncbi.nlm.nih.gov/pubmed/28592925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-017-9156-y
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