Engineering biomimetic periosteum with β-TCP scaffolds to promote bone formation in calvarial defects of rats

BACKGROUND: There is a critical need for the management of large bone defects. The purpose of this study was to engineer a biomimetic periosteum and to combine this with a macroporous β-tricalcium phosphate (β-TCP) scaffold for bone tissue regeneration. METHODS: Rat bone marrow-derived mesenchymal s...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Zhang, Dan, Gao, Peng, Li, Qin, Li, Jinda, Li, Xiaojuan, Liu, Xiaoning, Kang, Yunqing, Ren, Liling
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460346/
https://ncbi.nlm.nih.gov/pubmed/28583167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0592-4
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