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Structural Modeling of Chromatin Integrates Genome Features and Reveals Chromosome Folding Principle

How chromosomes fold into 3D structures and how genome functions are affected or even controlled by their spatial organization remain challenging questions. Hi-C experiment has provided important structural insights for chromosome, and Hi-C data are used here to construct the 3D chromatin structure...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xie, Wen Jun, Meng, Luming, Liu, Sirui, Zhang, Ling, Cai, Xiaoxia, Gao, Yi Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460185/
https://ncbi.nlm.nih.gov/pubmed/28588240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02923-6
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