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Chromatin remodeling by DNA bending, not twisting

Single-stranded regions (gaps) in nucleosomal DNA interfere with action of the RSC chromatin-remodeling complex, monitored by exposure of restriction endonuclease cutting sites. Single-strand breaks (nicks) in the DNA, by contrast, have no effect. Gaps on one side of the cutting site are inhibitory,...

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Autors principals: Lorch, Yahli, Davis, Barbara, Kornberg, Roger D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC546017/
https://ncbi.nlm.nih.gov/pubmed/15677336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409413102
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