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An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors
Collective cell migration is a common phenotype in epithelial cancers, which is associated with tumor cell metastasis and poor patient survival. However, the interplay between physiologically relevant pro-migratory stimuli and the underlying mechanical cell–cell interactions are poorly understood. W...
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Publié dans: | NPJ Syst Biol Appl |
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Auteurs principaux: | , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Nature Publishing Group UK
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460121/ https://ncbi.nlm.nih.gov/pubmed/28649432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0006-3 |
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