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Redesigning metabolism based on orthogonality principles
Modifications made during metabolic engineering for overproduction of chemicals have network-wide effects on cellular function due to ubiquitous metabolic interactions. These interactions, that make metabolic network structures robust and optimized for cell growth, act to constrain the capability of...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5459945/ https://ncbi.nlm.nih.gov/pubmed/28555623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15188 |
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