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Mild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss

The axon initial segment (AIS) is the site of action potential (AP) initiation, thus a crucial regulator of neuronal activity. In excitatory pyramidal neurons, the high density of voltage-gated sodium channels (NaV1.6) at the distal AIS regulates AP initiation. A surrogate AIS marker, ankyrin-G (ank...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Vascak, Michal, Sun, Jianli, Baer, Matthew, Jacobs, Kimberle M., Povlishock, John T.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459898/
https://ncbi.nlm.nih.gov/pubmed/28634442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00157
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