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Synthetic surfactant- and cross-linker-free preparation of highly stable lipid-polymer hybrid nanoparticles as potential oral delivery vehicles

The toxicity associated with concentrated synthetic surfactants and the poor stability at gastrointestinal condition are two major constraints for practical applications of solid lipid nanoparticles (SLN) as oral delivery vehicles. In this study, a synthetic surfactant-free and cross-linker-free met...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Taoran, Xue, Jingyi, Hu, Qiaobin, Zhou, Mingyong, Chang, Chao, Luo, Yangchao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459848/
https://ncbi.nlm.nih.gov/pubmed/28584240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02867-x
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