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Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations

Understanding the cellular-molecular substrates of heart disease is key to the development of cardiac specific therapies and to the prevention of off-target effects by non-cardiac targeted drugs. One of the primary targets for therapeutic intervention has been the human ether a go-go (hERG) K(+) cha...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Ocorr, Karen, Zambon, Alexander, Nudell, Yoav, Pineda, Santiago, Diop, Soda, Tang, Min, Akasaka, Takeshi, Taylor, Erika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459509/
https://ncbi.nlm.nih.gov/pubmed/28542428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006786
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