Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hyperalgesia of inflamed TMJ

BACKGROUND: Temporomandibular disorders (TMDs) have the highest prevalence in women of reproductive age. The role of estrogen in TMDs and especially in TMDs related pain is not fully elucidated. Voltage-gated sodium channel 1.7 (Nav1.7) plays a prominent role in pain perception and Nav1.7 in trigemi...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Bi, Rui-Yun, Meng, Zhen, Zhang, Peng, Wang, Xue-Dong, Ding, Yun, Gan, Ye-Hua
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459440/
https://ncbi.nlm.nih.gov/pubmed/28582470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178589
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы