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Quantitative Imaging of Single Live Cells Reveals Spatiotemporal Dynamics of Multistep Signaling Events of Chemoattractant Gradient Sensing in Dictyostelium

Activation of G-protein-coupled chemoattractant receptors triggers dissociation of Gα and Gβγ subunits. These subunits induce intracellular responses that can be highly polarized when a cell experiences a gradient of chemoattractant. Exactly how a cell achieves this amplified signal polarization is...

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Detalhes bibliográficos
Main Authors: Xu, Xuehua, Meier-Schellersheim, Martin, Jiao, Xuanmao, Nelson, Lauren E., Jin, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545903/
https://ncbi.nlm.nih.gov/pubmed/15563608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-07-0544
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