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The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo

Redox signaling is important for embryogenesis, guiding pathways that govern processes crucial for embryo patterning, including cell polarization, proliferation, and apoptosis. Exposure to pro-oxidants during this period can be deleterious, resulting in altered physiology, teratogenesis, later-life...

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Publicat a:Redox Biol
Autors principals: Sant, Karilyn E., Hansen, Jason M., Williams, Larissa M., Tran, Nancy L., Goldstone, Jared V., Stegeman, John J., Hahn, Mark E., Timme-Laragy, Alicia
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458767/
https://ncbi.nlm.nih.gov/pubmed/28582729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.05.023
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