The Cell Cycle Inhibitors p21(Cip1) and p27(Kip1) Control Proliferation but Enhance DNA Damage Resistance of Glioma Stem Cells

High-grade gliomas are the most prevalent and lethal primary brain tumors. They display a hierarchical arrangement with a population of self-renewing and highly tumorigenic cells called cancer stem cells. These cells are thought to be responsible for tumor recurrence, which make them main candidates...

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Vydáno v:Neoplasia
Hlavní autoři: Morris-Hanon, Olivia, Furmento, Verónica Alejandra, Rodríguez-Varela, María Soledad, Mucci, Sofía, Fernandez-Espinosa, Damián Darío, Romorini, Leonardo, Sevlever, Gustavo Emilio, Scassa, María Elida, Videla-Richardson, Guillermo Agustín
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2017
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458648/
https://ncbi.nlm.nih.gov/pubmed/28582703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.04.001
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