Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia

INTRODUCTION: Preeclampsia is a leading cause of maternal and fetal mortality worldwide, yet its exact pathogenesis remains elusive. OBJECTIVES: This study, nested within the Vitamin D Antenatal Asthma Reduction Trial (VDAART), aimed to develop integrated omics models of preeclampsia that have utili...

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Vydáno v:Metabolomics
Hlavní autoři: Kelly, Rachel S., Croteau-Chonka, Damien C., Dahlin, Amber, Mirzakhani, Hooman, Wu, Ann C., Wan, Emily S., McGeachie, Michael J., Qiu, Weiliang, Sordillo, Joanne E., Al-Garawi, Amal, Gray, Kathryn J., McElrath, Thomas F., Carey, Vincent J., Clish, Clary B., Litonjua, Augusto A., Weiss, Scott T., Lasky-Su, Jessica A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458629/
https://ncbi.nlm.nih.gov/pubmed/28596717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1149-8
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