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Reconstitution of uridine-deletion precleaved RNA editing with two recombinant enzymes

Uridine insertion/deletion RNA editing in trypanosomatid mitochondria is a posttranscriptional RNA modification phenomenon required for translation of mitochondrial mRNAs. This process involves guide RNA-mediated cleavage at a specific site, insertion or deletion of Us from the 3′ end of the 5′ mRNA...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kang, Xuedong, Rogers, Kestrel, Gao, Guanghan, Falick, Arnold M., Zhou, Sharleen, Simpson, Larry
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545852/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15657144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409275102
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