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Crystal structure of Rv1220c, a SAM-dependent O-methyltransferase from Mycobacterium tuberculosis

Rv1220c from Mycobacterium tuberculosis is annotated as an O-methyltransferase (MtbOMT). Currently, no structural information is available for this protein. Here, the crystal structure of MtbOMT refined to 2.0 Å resolution is described. The structure reveals the presence of a methyltransferase fold...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Yan, Qiaoling, Shaw, Neil, Qian, Lanfang, Jiang, Dunquan
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458387/
https://ncbi.nlm.nih.gov/pubmed/28580918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17006057
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