Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

Flk-1 (human counterpart, KDR) tyrosine kinase, which is one of the two VEGF receptors, is crucial for vascular development. Recently, we showed that, among tyrosine residues of KDR, tyrosine residues 1175 (Y1175, corresponding to Y1173 in murine Flk-1) and Y1214 (Y1212 in Flk-1) are autophosphoryla...

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Библиографические подробности
Главные авторы: Sakurai, Yoshiko, Ohgimoto, Kaori, Kataoka, Yuki, Yoshida, Nobuaki, Shibuya, Masabumi
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC545830/
https://ncbi.nlm.nih.gov/pubmed/15644447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404984102
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