Stat3 phosphorylation is required for embryonic stem cells ground state maintenance in 2i culture media

Embryonic stem cells (ES cells) can be maintained its undifferentiated state with feeder cells or LIF, which can activate Jak/Stat3 pathway. Recently, it has been reported a new culture condition comprising serum-free medium with ERK and GSK3β inhibitors (2i) could drive ES cells into a state of plu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Dan, Sang, Hui, Zhang, Kaiyue, Nie, Yan, Zhao, Shuang, Zhang, Yan, He, Ningning, Wang, Yuebing, Xu, Yang, Xie, Xiaoyan, Li, Zongjin, Liu, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458203/
https://ncbi.nlm.nih.gov/pubmed/28415722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16112
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