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Structural insights into the EB1–APC interaction

EB1 proteins bind to microtubule ends where they act in concert with other components, including the adenomatous polyposis coli (APC) tumor suppressor, to regulate the microtubule filament system. We find that EB1 is a stable dimer with a parallel coiled coil and show that dimerization is essential...

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Detalhes bibliográficos
Main Authors: Honnappa, Srinivas, John, Corinne M, Kostrewa, Dirk, Winkler, Fritz K, Steinmetz, Michel O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545816/
https://ncbi.nlm.nih.gov/pubmed/15616574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600529
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