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Structural insights into the EB1–APC interaction
EB1 proteins bind to microtubule ends where they act in concert with other components, including the adenomatous polyposis coli (APC) tumor suppressor, to regulate the microtubule filament system. We find that EB1 is a stable dimer with a parallel coiled coil and show that dimerization is essential...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545816/ https://ncbi.nlm.nih.gov/pubmed/15616574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600529 |
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