Ameliorative Effects of Nilotinib on CCl4 Induced Liver Fibrosis Via Attenuation of RAGE/HMGB1 Gene Expression and Oxidative Stress in Rat

Nilotinib as a tyrosine kinase inhibitor has been recently used to improve the liver fibrosis process, but the exact mechanisms still require further clarification. In this study, we investigated the anti-fibrotic effects of Nilotinib via RAGE/HMGB1axis and antioxidant mechanisms. This experimental...

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Dettagli Bibliografici
Pubblicato in:Chonnam Med J
Autori principali: Khanjarsim, Vahid, Karimi, Jamshid, Khodadadi, Iraj, Mohammadalipour, Adel, Goodarzi, Mohammad Taghi, Solgi, Ghasem, Hashemnia, Mohammad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Chonnam National University Medical School 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457946/
https://ncbi.nlm.nih.gov/pubmed/28584790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4068/cmj.2017.53.2.118
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