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Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach

An increasing number of cases of herb-induced liver injury (HILI) have been reported, presenting new clinical challenges. In this study, taking Polygonum multiflorum Thunb (PmT) as an example, we proposed a computational systems toxicology approach to explore the molecular mechanisms of HILI. First,...

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Détails bibliographiques
Publié dans:Acta Pharmacol Sin
Auteurs principaux: Wang, Yin-yin, Li, Jie, Wu, Zeng-rui, Zhang, Bo, Yang, Hong-bin, Wang, Qin, Cai, Ying-chun, Liu, Gui-xia, Li, Wei-hua, Tang, Yun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457689/
https://ncbi.nlm.nih.gov/pubmed/28239160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.147
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