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Patterns of relapse in primary central nervous system lymphoma: inferences regarding the role of the neuro-vascular unit and monoclonal antibodies in treating occult CNS disease

BACKGROUND AND PURPOSE: The radiologic features and patterns of primary central nervous system lymphoma (PCNSL) at initial presentation are well described. High response rates can be achieved with first-line high-dose methotrexate (HD-MTX) based regimens, yet many relapse within 2 years of diagnosis...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Ambady, Prakash, Fu, Rongwei, Netto, Joao Prola, Kersch, Cymon, Firkins, Jenny, Doolittle, Nancy D., Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457655/
https://ncbi.nlm.nih.gov/pubmed/28577579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0064-3
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