Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1

Although lysyl oxidase-like 1 (LOXL1) is known as the principal genetic risk factor for pseudoexfoliation (PEX) syndrome, a major cause of glaucoma and cardiovascular complications, no functional variants have been identified to date. Here, we conduct a genome-wide association scan on 771 German PEX...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Pasutto, Francesca, Zenkel, Matthias, Hoja, Ursula, Berner, Daniel, Uebe, Steffen, Ferrazzi, Fulvia, Schödel, Johannes, Liravi, Panah, Ozaki, Mineo, Paoli, Daniela, Frezzotti, Paolo, Mizoguchi, Takanori, Nakano, Satoko, Kubota, Toshiaki, Manabe, Shinichi, Salvi, Erika, Manunta, Paolo, Cusi, Daniele, Gieger, Christian, Wichmann, Heinz-Erich, Aung, Tin, Khor, Chiea Chuen, Kruse, Friedrich E., Reis, André, Schlötzer-Schrehardt, Ursula
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457519/
https://ncbi.nlm.nih.gov/pubmed/28534485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15466
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker